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IN VITRO DEGRADATION AND EROSION OF DEGRADABLE LACTATE SEGMENTED POLYURETHANES

V. Melnig1,* , L. Obreja1, A. Garlea1

Affiliation

  1. Faculty of Physics, “Al. I. Cuza” University, Bd. Carol I, Nr. 11A, Iasi, 700506, Romania

Abstract

A significant number of studies for improving the biocompatibility of polyurethanes have been concentrated on bulk and surface modifications. In this view, the knowledge of polymer degradation in body solvent-fluids (aqua), and the subsequent physical properties changes, is the first step for a better designing of polyurethanes used in biomedical applications. In this paper, the dynamics of water non-enzymatic hydrolysis of poly(lactateurethane) are analysed and the results revealed characteristics more suitable for biomedical applications, than poly(esterurethane) materials, due to the incorporation of a soft lactate segment..

Keywords

Poly(lactateurethane), Poly(esterurethane), Water hydrolysis, Erosion-diffusion mechanism.

Submitted at: Oct. 5, 2005
Accepted at: Nov. 24, 2005

Citation

V. Melnig, L. Obreja, A. Garlea, IN VITRO DEGRADATION AND EROSION OF DEGRADABLE LACTATE SEGMENTED POLYURETHANES, Journal of Optoelectronics and Advanced Materials Vol. 7, Iss. 6, pp. 2803-2808 (2005)