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A simple continuous-wave diffuse optical tomography system for parametric investigation of different tissue phantoms

M. PATACHIA1

Affiliation

  1. Department of Lasers, National Institute for Laser, Plasma and Radiation Physics, 409 Atomistilor St., PO Box MG-36, 077125 Magurele, Ilfov, Romania

Abstract

Diffuse optical tomography (DOT) is a potential diagnostic tool for detecting abnormal growths in translucent soft tissues. Its principle is to use multiple movable light sources and detectors attached to the tissue surface to collect information on light attenuation, and to reconstruct the internal 3-D absorption and scattering distributions. The development of optical imaging techniques, like that of any other medical diagnostic modality, has relied upon appropriate phantoms whose physical properties and geometries are matched to those of human tissues. Measurements on phantoms are used to evaluate the performance of systems and to validate the imaging algorithms. Together with the reconstructions of the tissues structure, the calibration is the pivotal part of the data acquisition due to the variation in characteristics of each laser source, optical fibres, detectors, and optic elements. An accurate calibration is achieved in a homogeneous phantom. The work describes some methods to achieve homogeneous phantoms and how they are used to evaluate the performance of the system..

Keywords

Laser Diode, Diffuse optical tomography, Optics fibre, Tissue phantom, Image reconstruction.

Submitted at: Nov. 14, 2012
Accepted at: April 11, 2013

Citation

M. PATACHIA, A simple continuous-wave diffuse optical tomography system for parametric investigation of different tissue phantoms, Journal of Optoelectronics and Advanced Materials Vol. 15, Iss. 3-4, pp. 155-163 (2013)