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Comparative evaluation of the influence of two resinbased restorative materials on the behaviour of progenitor-like cells

A. ROMAN1,* , A. SOANCA1, L. BARBU-TUDORAN2, A. I. IRIMIE1, E. PÁLL3

Affiliation

  1. Faculty of Dental Medicine, ”Iuliu Haţieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
  2. Electronic Microscopy Centre , Babeş-Bolyai University, 400006 Cluj-Napoca, Romania
  3. Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania

Abstract

The aim of the present study was to investigate the biological effects of two resin-based restorative dental materials placed in direct contact with cells isolated from palatal connective tissue graft (CTG) and to demonstrate that the harvested palatal CTG contained progenitor cells. Palatal cells were isolated from tissues collected from individuals undergoing periodontal surgeries. Composite resin and compomer discs plated with ex vivo expanded cells were used to analyze the cell characteristics by scanning electron microscopy (SEM). The amount of the inorganic filler of the two dental materials was determined by thermogravimetric (TGA) analysis. The composite resin had a relatively smaller amount of inorganic filler and was quite stable above 750 °C in comparison with the glass ionomer-resin composite. Resin composite and compomer materials seemed to have no cytotoxic effect on isolated cells since the cells had grown well on both restorative materials. Over the entire cultivation period, the cells remained undifferentiated and did not change the phenotype, which sustained that they are undifferentiated cell types..

Keywords

Composite resin, Restoration, Progenitor cell, Monomer.

Submitted at: April 9, 2012
Accepted at: June 6, 2012

Citation

A. ROMAN, A. SOANCA, L. BARBU-TUDORAN, A. I. IRIMIE, E. PÁLL, Comparative evaluation of the influence of two resinbased restorative materials on the behaviour of progenitor-like cells, Journal of Optoelectronics and Advanced Materials Vol. 14, Iss. 5-6, pp. 491-496 (2012)