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Dual mode SDOCT-HSI approach for cancer surgery guidance

D. SAVASTRU1, S. MICLOS1,* , N. IFTIMIA2, M. A. CALIN1, R. SAVASTRU1, D. MANEA1, S. DONTU1

Affiliation

  1. National Institute of R&D for Optoelectronics - INOE 2000, 409 Atomistilor St., Magurele, Ilfov, RO-077125, Romania
  2. Physical Sciences, Inc., 20 New England Business Ctr. Drive, Andover, MA-01810, USA

Abstract

An innovative approach for guiding cancer surgery is proposed in this paper. Spectral-Domain Optical Coherence Tomography (SDOCT) and Hyperspectral Imaging (HSI) are combined with the goal of taking advantage of the complementary capabilities provided by each technique: spatial (3D) information at the micron scale and spectral signatures of the biological specimens. The proposed approach offers the potential to solve a major dilemma that every surgeon has to address in the operating room: “are surgical margins free from any outbreak of cancer?”. Preliminary results of this work on excised specimens indicate that combined SDOCT-HSI imaging enables reliable detection of cancer presence and therefore it might be used in the future as a clinical tool for differentiating positive margins during surgery..

Keywords

Optical coherence tomography, Hyperspectral imaging, Surgery guidance, Tumour margins.

Submitted at: Oct. 4, 2016
Accepted at: Nov. 25, 2016

Citation

D. SAVASTRU, S. MICLOS, N. IFTIMIA, M. A. CALIN, R. SAVASTRU, D. MANEA, S. DONTU, Dual mode SDOCT-HSI approach for cancer surgery guidance, Journal of Optoelectronics and Advanced Materials Vol. 18, Iss. 11-12, pp. 993-999 (2016)