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Estimation of the antioxidant activity of flavonoids by isothermal chemiluminescence method

D. A. MARIS1, M. MARIS1, S. JIPA2,3,* , T. ZAHARESCU2, W. KAPPEL2, A. MANTSCH2, M. LUNGULESCU2

Affiliation

  1. Ovidius University, Faculty of Stomatology, 124 Mamaia Blvd, 900527, Constanta, Romania
  2. INCDIE ICPE CA, 313 Splaiul Unirii P. O. Box 149, Bucharest 030138, Romania
  3. “Valachia” University of Targoviste, 18-22 Unirii Av., Targoviste 130082, Romania

Abstract

The correlation between the structural characteristics of some representative classes of flavonoids and their antioxidant activity was studied. A simple method based on isothermal CL measurements for estimating the antioxidant activity of flavonoids was used. The obtained results suggest that antioxidant activity depends both on substitution pattern of hydroxyl groups of the flavonoid skeleton and the presence of unsaturation at the C2 – C3 bond. Quercetin showed the highest antioxidant activity among tested compounds.The ability of some flavonoids to block organic peroxyl radicals was found to be comparable with butylhydroxytoluene (BHT)..

Keywords

Flavonoids, Antioxidant activity, Chemiluminescence, Structure-activity relationship.

Submitted at: Nov. 2, 2008
Accepted at: Dec. 10, 2008

Citation

D. A. MARIS, M. MARIS, S. JIPA, T. ZAHARESCU, W. KAPPEL, A. MANTSCH, M. LUNGULESCU, Estimation of the antioxidant activity of flavonoids by isothermal chemiluminescence method, Journal of Optoelectronics and Advanced Materials Vol. 10, Iss. 12, pp. 3364-3367 (2008)