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Measurement of the modifications of Polidocanol absorption spectra after exposure to NIR laser radiation

A. SMARANDACHE1,* , M. TRELLES2, M. L. PASCU1

Affiliation

  1. National Institute for Laser, Plasma and Radiation Physics, Laser Department, P.O.Box, MG-36, 077125, Bucharest, Romania
  2. Instituto Médico Vilafortuny/FUNDACION ANTONI DE GIMBERNAT, Cambrils, Spain

Abstract

Polidocanol (commercially available under the name Aetoxisclerol) is one of the medicines used in the treatment of varicose veins diseases. It seems that exposure of tissues impregnated with Polidocanol to Nd:YAG laser radiation at 1.06μm improves the treatment efficiency. Because the commercially available Aetoxisclerol is a mixture of substances, when it is exposed to laser radiation, one should consider the interaction with all the compounds. The absorption spectra in UV-VISNIR spectral ranges are measured for Aetoxisclerol. We exposed it at pulsed Nd:YAG laser beam between 2-30 min at known irradiation doses. The possible mechanisms implied in improvement of the efficiency of Polidocanol are discussed..

Keywords

Sclerotherapy, Polidocanol, Laser, Optical absorption spectra.

Submitted at: July 12, 2010
Accepted at: Sept. 15, 2010

Citation

A. SMARANDACHE, M. TRELLES, M. L. PASCU, Measurement of the modifications of Polidocanol absorption spectra after exposure to NIR laser radiation, Journal of Optoelectronics and Advanced Materials Vol. 12, Iss. 9, pp. 1942-1945 (2010)