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Study of iron oxide nanoparticles coated with dextrin obtained by coprecipitation

R. A. VATASESCU-BALCAN1, D. PREDOI2,* , F. UNGUREANU2, M. COSTACHE1

Affiliation

  1. Molecular Biology Center, University of Bucharest, 91-95 Splaiul Independenţei, 76201, Bucharest 5, Romania
  2. National Institute for Physics of Materials, P.O. Box MG 07, Bucharest, Magurele, Romania

Abstract

In this paper we present the preparation and biological tests of iron oxide nanoparticles coated with dextrin. Iron oxide was also prepared by co-precipitation. The samples were characterized by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). Biocompatibility test of the iron oxide nanoparticles coated with dextrin substrate has been done using primary osteoblast cell line. After osteoblast culture achievement, the cells were treated with trypsin 0.05% and splitted in 35/35 mm Petri dish. The influence in vitro was assessed using primary osteoblast cell line and various techniques to observe cell-particles interactions. The results of these analyses are presented in this work..

Keywords

Magnetic nanoparticles, Dextrin, Cell culture, Cell viability, TEM, SEM.

Submitted at: Sept. 25, 2007
Accepted at: March 17, 2008

Citation

R. A. VATASESCU-BALCAN, D. PREDOI, F. UNGUREANU, M. COSTACHE, Study of iron oxide nanoparticles coated with dextrin obtained by coprecipitation, Journal of Optoelectronics and Advanced Materials Vol. 10, Iss. 3, pp. 693-696 (2008)